| Protocol ID | NCT01081899 |
| Registration Date | 2010-03-05 |
| Status | completed |
| Sponsor | Regional Palliative Care Network |
| Country | Italy |
| Industry | not industry |
| Blinding | unblinded |
| Center Type | singel-center RCT |
| Scope | national RCT |
| First Patient In | 2009-11-01 |
| Last Patient Out | 2012-10-01 |
| Publication | n |
| Gender % | ALL |
| Mean Age | 18 Years - |
NCT01081899
The Effectiveness of the Liverpool Care Pathway in Improving End of Life Care for Dying Cancer Patients in Hospital. A Cluster Randomised Trial.
| Field |
CLAUDE
claude-sonnet-4-20250514 Thinking: claude-opus-4-20250514 5241ms / 10170 tok |
GLM
glm-5.1 9809ms / 8934 tok |
OPENAI
gpt-4o Thinking: o3 6670ms / 8795 tok |
Review |
|---|---|---|---|---|
| rct_type | Cluster RCT | Cluster RCT | Cluster RCT | OK |
| cancer_status | Cancer | Cancer | Cancer | OK |
| non_cancer_spec | N/A | N/A | N/A | OK |
| setting_patient | inpatient | inpatient | inpatient | OK |
| setting_place | hospital | hospital | hospital | OK |
| feasibility | fully powered RCT | fully powered RCT | fully powered RCT | OK |
| intervention_pharmacologic | no | no | no | OK |
| intervention_chemo_immuno_radio | no | no | no | OK |
| intervention_complementary | no | no | no | OK |
| intervention_device | no | no | no | OK |
| intervention_psychological | no | no | no | OK |
| intervention_complex |
yes
yes → yes
shaky reasoning✓ Unanimous
Initial: yes
Requery: yes — The LCP-I Program is a continuous quality improvement program that combines multiple interacting components including training for healthcare professionals, care pathways implementation, and systematic quality improvement processes targeting different aspects of end-of-life care.
|
yes
yes
shaky reasoning✓ Unanimous
Initial: yes
|
yes
no → yes
shaky reasoning✓ Unanimous
Initial: no
Requery: yes — The LCP-I Program is a complex intervention involving quality improvement, professional training, and organizational change for end-of-life care.
|
OK |
| intervention_acp | no | no | no | OK |
| intervention_music | no | no | no | OK |
| intervention_screening | no | no | no | OK |
| intervention_palliative | yes | yes | yes | OK |
| intervention_education |
yes
yes → yes → yes
shaky reasoning✓ Unanimous
Initial: yes
Requery: yes — The intervention is the LCP-I Program which includes intensive training of healthcare professionals on end-of-life care pathways as its primary component.
Thinking: yes — The LCP-I Program is a healthcare professional training intervention that involves intensive training of ward staff over 6 months to improve end-of-life care practices.
|
yes
yes → no
shaky reasoning✓ Unanimous
Initial: yes
Requery: no — The LCP-I Program is a continuous quality improvement program implemented by a Palliative Care Unit (a complex organizational/system-level intervention), which involves training as an implementation method rather than being a primary educational intervention itself.
|
yes
no → no → yes
shaky reasoning✓ Unanimous
Initial: no
Requery: no — The primary focus of the LCP-I Program is quality improvement in end-of-life care, not primarily education or training-based intervention.
Thinking: yes — The LCP-I intervention is chiefly an intensive training and implementation program that educates hospital staff on end-of-life care practices.
|
OK |
| intervention_digital | no | no | no | OK |
| intervention_other | no | no | no | OK |
| outcome_symptom | yes | yes | yes | OK |
| outcome_qol | yes | yes | yes | OK |
| outcome_dignity | no | no | no | OK |
| outcome_cost |
no
no → no
shaky reasoning✓ Unanimous
Initial: no
Requery: no — The study focuses on quality of end-of-life care measures through patient/family satisfaction surveys and clinical outcomes without measuring costs, healthcare utilization, or economic endpoints.
|
no
yes → no
shaky reasoning✓ Unanimous
Initial: yes
Requery: no — The trial focuses on measuring the quality of end-of-life care, communication, and symptom control without assessing cost-effectiveness, healthcare utilization costs, or resource use.
|
no
no → no
shaky reasoning✓ Unanimous
Initial: no
Requery: no — The trial focuses on improving the quality of end-of-life care without addressing cost-effectiveness or resource utilization.
|
OK |
| outcome_other | yes | yes | yes | OK |
| pharmacologic_sub | N/A | N/A | N/A | OK |