NCT01081899

The Effectiveness of the Liverpool Care Pathway in Improving End of Life Care for Dying Cancer Patients in Hospital. A Cluster Randomised Trial.

Extracted Fields (from Registry)
Protocol IDNCT01081899
Registration Date2010-03-05
Statuscompleted
SponsorRegional Palliative Care Network
CountryItaly
Industrynot industry
Blindingunblinded
Center Typesingel-center RCT
Scopenational RCT
First Patient In2009-11-01
Last Patient Out2012-10-01
Publicationn
Gender %ALL
Mean Age18 Years -
LLM Classifications (Side-by-Side)
Field CLAUDE
claude-sonnet-4-20250514
Thinking: claude-opus-4-20250514
5241ms / 10170 tok
GLM
glm-5.1
9809ms / 8934 tok
OPENAI
gpt-4o
Thinking: o3
6670ms / 8795 tok
Review
rct_type Cluster RCT Cluster RCT Cluster RCT OK
cancer_status Cancer Cancer Cancer OK
non_cancer_spec N/A N/A N/A OK
setting_patient inpatient inpatient inpatient OK
setting_place hospital hospital hospital OK
feasibility fully powered RCT fully powered RCT fully powered RCT OK
intervention_pharmacologic no no no OK
intervention_chemo_immuno_radio no no no OK
intervention_complementary no no no OK
intervention_device no no no OK
intervention_psychological no no no OK
intervention_complex yes yes → yes
shaky reasoning
✓ Unanimous Initial: yes Requery: yes — The LCP-I Program is a continuous quality improvement program that combines multiple interacting components including training for healthcare professionals, care pathways implementation, and systematic quality improvement processes targeting different aspects of end-of-life care.
yes yes
shaky reasoning
✓ Unanimous Initial: yes
yes no → yes
shaky reasoning
✓ Unanimous Initial: no Requery: yes — The LCP-I Program is a complex intervention involving quality improvement, professional training, and organizational change for end-of-life care.
OK
intervention_acp no no no OK
intervention_music no no no OK
intervention_screening no no no OK
intervention_palliative yes yes yes OK
intervention_education yes yes → yes → yes
shaky reasoning
✓ Unanimous Initial: yes Requery: yes — The intervention is the LCP-I Program which includes intensive training of healthcare professionals on end-of-life care pathways as its primary component. Thinking: yes — The LCP-I Program is a healthcare professional training intervention that involves intensive training of ward staff over 6 months to improve end-of-life care practices.
yes yes → no
shaky reasoning
✓ Unanimous Initial: yes Requery: no — The LCP-I Program is a continuous quality improvement program implemented by a Palliative Care Unit (a complex organizational/system-level intervention), which involves training as an implementation method rather than being a primary educational intervention itself.
yes no → no → yes
shaky reasoning
✓ Unanimous Initial: no Requery: no — The primary focus of the LCP-I Program is quality improvement in end-of-life care, not primarily education or training-based intervention. Thinking: yes — The LCP-I intervention is chiefly an intensive training and implementation program that educates hospital staff on end-of-life care practices.
OK
intervention_digital no no no OK
intervention_other no no no OK
outcome_symptom yes yes yes OK
outcome_qol yes yes yes OK
outcome_dignity no no no OK
outcome_cost no no → no
shaky reasoning
✓ Unanimous Initial: no Requery: no — The study focuses on quality of end-of-life care measures through patient/family satisfaction surveys and clinical outcomes without measuring costs, healthcare utilization, or economic endpoints.
no yes → no
shaky reasoning
✓ Unanimous Initial: yes Requery: no — The trial focuses on measuring the quality of end-of-life care, communication, and symptom control without assessing cost-effectiveness, healthcare utilization costs, or resource use.
no no → no
shaky reasoning
✓ Unanimous Initial: no Requery: no — The trial focuses on improving the quality of end-of-life care without addressing cost-effectiveness or resource utilization.
OK
outcome_other yes yes yes OK
pharmacologic_sub N/A N/A N/A OK
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