NCT01474642

A Randomized Phase II Trial of Capecitabine Plus Cisplatin (XP) Versus Capecitabine Plus Genexol (XG) as a First-line Treatment for Advanced or Recurrent Esophageal Squamous Cell Carcinoma

Extracted Fields (from Registry)
Protocol IDNCT01474642
Registration Date2011-11-18
Statuscompleted
SponsorSamsung Medical Center
CountrySouth Korea
Industrynot industry
Blindingunblinded
Center Typesingel-center RCT
Scopenational RCT
First Patient In2008-09-01
Last Patient Out2014-05-01
Publicationn
Gender %ALL
Mean Age18 Years -
LLM Classifications (Side-by-Side)
Field CLAUDE
claude-sonnet-4-20250514
Thinking: claude-opus-4-20250514
4726ms / 10571 tok
OPENAI
gpt-4o
Thinking: o3
4598ms / 8997 tok
GLM
glm-5.1
11134ms / 9183 tok
Review
rct_type parallel RCT parallel RCT parallel RCT OK
cancer_status Cancer Cancer Cancer OK
non_cancer_spec N/A N/A N/A OK
setting_patient outpatient outpatient outpatient OK
setting_place other other → hospital → other
shaky reasoning
✓ Unanimous Initial: other Requery: hospital — The trial involves IV chemotherapy administration (cisplatin 75mg/m2 iv, paclitaxel 80mg/m2 iv) requiring hospital-based infusion services for cancer patients with advanced/metastatic disease. Thinking: other — This is outpatient chemotherapy where patients receive IV infusions at clinic visits and take oral medication at home, not requiring hospital admission.
other hospital → other → other
shaky reasoning
✓ Unanimous Initial: hospital Requery: other — The intervention involves outpatient administration of chemotherapy drugs (Capecitabine and Cisplatin/Paditaxel), which does not require hospitalization or inpatient admission, fitting 'other' as the setting place. Thinking: other — IV/PO chemotherapy is administered in an outpatient oncology clinic at Samsung Medical Center, not requiring inpatient admission.
other other → other
shaky reasoning
✓ Unanimous Initial: other Requery: other — The intervention involves outpatient chemotherapy regimens for advanced cancer, which is delivered in an outpatient clinic or ambulatory care setting rather than requiring inpatient hospital admission.
OK
feasibility fully powered RCT fully powered RCT fully powered RCT OK
intervention_pharmacologic yes yes yes OK
intervention_chemo_immuno_radio yes yes yes OK
intervention_complementary no no no OK
intervention_device no no no OK
intervention_psychological no no no OK
intervention_complex no no no OK
intervention_acp no no no OK
intervention_music no no no OK
intervention_screening no no no OK
intervention_palliative no no no OK
intervention_education no no no OK
intervention_digital no no no OK
intervention_other no no no OK
outcome_symptom no no no OK
outcome_qol yes yes yes OK
outcome_dignity no no no OK
outcome_cost no no no OK
outcome_other yes yes yes OK
pharmacologic_sub chemotherapy chemotherapy chemotherapy OK
Back to Studies