| Protocol ID | NCT01722344 |
| Registration Date | 2012-11-06 |
| Status | completed |
| Sponsor | Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital |
| Country | Denmark |
| Industry | not industry |
| Blinding | blinded |
| Center Type | singel-center RCT |
| Scope | national RCT |
| First Patient In | 2012-10-01 |
| Last Patient Out | 2019-02-01 |
| Publication | n |
| Gender % | ALL |
| Mean Age | 18 Years - 64 Years |
NCT01722344
Individual Placement and Support (IPS) Enhanced With Cognitive Remediation and Social Skills Training in Denmark: a Randomized Controlled Trial
| Field |
OPENAI
gpt-4o Thinking: o3 3287ms / 8899 tok |
GLM
glm-5.1 6380ms / 9043 tok |
CLAUDE
claude-sonnet-4-20250514 Thinking: claude-opus-4-20250514 4967ms / 10351 tok |
Review |
|---|---|---|---|---|
| rct_type | parallel RCT | parallel RCT | parallel RCT | OK |
| cancer_status | non-cancer | non-cancer | non-cancer | OK |
| non_cancer_spec | N/A | N/A | N/A | OK |
| setting_patient | outpatient | outpatient | outpatient | OK |
| setting_place | other | other | other | OK |
| feasibility | fully powered RCT | fully powered RCT | fully powered RCT | OK |
| intervention_pharmacologic | no | no | no | OK |
| intervention_chemo_immuno_radio | no | no | no | OK |
| intervention_complementary | no | no | no | OK |
| intervention_device | no | no | no | OK |
| intervention_psychological |
no
no → no
shaky reasoning✓ Unanimous
Initial: no
Requery: no — The intervention includes cognitive remediation and social skills training, which are not structured psychological therapies like CBT or psychotherapy.
|
yes |
no
yes → no
shaky reasoning✓ Unanimous
Initial: yes
Requery: no — The interventions focus on vocational rehabilitation, cognitive remediation (training), and social skills training, which are behavioral/educational approaches rather than structured psychological therapies like CBT or psychotherapy.
|
– |
| intervention_complex | yes | yes | yes | OK |
| intervention_acp | no | no | no | OK |
| intervention_music | no | no | no | OK |
| intervention_screening | no | no | no | OK |
| intervention_palliative | no | no | no | OK |
| intervention_education |
no
no → no → yes
shaky reasoning✗ No consensus
Initial: no
Requery: no — The primary component of the trial is vocational intervention (IPS), with cognitive remediation and social skills training as enhancements, rather than primarily an educational or training program.
Thinking: yes — Interventions centre on delivering structured cognitive remediation and work-related social skills training sessions, i.e., patient training as a primary component.
|
yes |
yes
yes → yes → no
shaky reasoning✗ No consensus
Initial: yes
Requery: yes — The study includes cognitive remediation and work-related social skills training as a primary intervention component, involving 24 sessions of computer-based cognitive training and 24 group sessions of cognitive coping strategies and skills training.
Thinking: no — This is primarily a vocational rehabilitation intervention focused on employment support (IPS), with cognitive training and social skills training as supplementary components to enhance employment outcomes, not as the primary intervention.
|
|
| intervention_digital |
yes
yes → yes → yes
shaky reasoning✗ No consensus
Initial: yes
Requery: yes — The core intervention includes 24 sessions of computer-based cognitive training, which is a digital component central to the IPS plus intervention.
Thinking: yes — The IPS-plus arm relies on computer-based cognitive remediation sessions, making digital technology a core component of that intervention.
|
no |
no
no → no → no
shaky reasoning✗ No consensus
Initial: no
Requery: no — While one arm includes computer-based cognitive training, the core intervention is Individual Placement and Support (IPS) which is an in-person vocational rehabilitation service delivered by employment specialists, making the digital component supplementary rather than the primary delivery mechanism.
Thinking: no — While one arm includes computer-based cognitive training, the core intervention is employment support delivered by human specialists, not technology.
|
|
| intervention_other |
no
no → yes → no
shaky reasoning✓ Unanimous
Initial: no
Requery: yes — The interventions involve behavioral approaches like vocational rehabilitation and cognitive/social skills training, which do not fit into the specified categories such as pharmacologic or device interventions.
Thinking: no — The trial uses behavioral mental-health therapies (IPS with cognitive remediation and social skills training), fitting the psychological category.
|
yes |
no
yes → yes → no
shaky reasoning✓ Unanimous
Initial: yes
Requery: yes — This intervention involves vocational rehabilitation and employment support services combined with cognitive remediation and social skills training, which do not fit into any of the specified intervention categories.
Thinking: no — The intervention includes psychological components (cognitive remediation, social skills training) and is a complex multi-component intervention.
|
– |
| outcome_symptom | yes | yes | yes | OK |
| outcome_qol | yes | yes | yes | OK |
| outcome_dignity | no | no | no | OK |
| outcome_cost | no | yes | no | – |
| outcome_other | yes | yes | yes | OK |
| pharmacologic_sub | N/A | N/A | N/A | OK |