NCT01722344

Individual Placement and Support (IPS) Enhanced With Cognitive Remediation and Social Skills Training in Denmark: a Randomized Controlled Trial

Extracted Fields (from Registry)
Protocol IDNCT01722344
Registration Date2012-11-06
Statuscompleted
SponsorMental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
CountryDenmark
Industrynot industry
Blindingblinded
Center Typesingel-center RCT
Scopenational RCT
First Patient In2012-10-01
Last Patient Out2019-02-01
Publicationn
Gender %ALL
Mean Age18 Years - 64 Years
LLM Classifications (Side-by-Side)
Field OPENAI
gpt-4o
Thinking: o3
3287ms / 8899 tok
GLM
glm-5.1
6380ms / 9043 tok
CLAUDE
claude-sonnet-4-20250514
Thinking: claude-opus-4-20250514
4967ms / 10351 tok
Review
rct_type parallel RCT parallel RCT parallel RCT OK
cancer_status non-cancer non-cancer non-cancer OK
non_cancer_spec N/A N/A N/A OK
setting_patient outpatient outpatient outpatient OK
setting_place other other other OK
feasibility fully powered RCT fully powered RCT fully powered RCT OK
intervention_pharmacologic no no no OK
intervention_chemo_immuno_radio no no no OK
intervention_complementary no no no OK
intervention_device no no no OK
intervention_psychological no no → no
shaky reasoning
✓ Unanimous Initial: no Requery: no — The intervention includes cognitive remediation and social skills training, which are not structured psychological therapies like CBT or psychotherapy.
yes no yes → no
shaky reasoning
✓ Unanimous Initial: yes Requery: no — The interventions focus on vocational rehabilitation, cognitive remediation (training), and social skills training, which are behavioral/educational approaches rather than structured psychological therapies like CBT or psychotherapy.
intervention_complex yes yes yes OK
intervention_acp no no no OK
intervention_music no no no OK
intervention_screening no no no OK
intervention_palliative no no no OK
intervention_education no no → no → yes
shaky reasoning
✗ No consensus Initial: no Requery: no — The primary component of the trial is vocational intervention (IPS), with cognitive remediation and social skills training as enhancements, rather than primarily an educational or training program. Thinking: yes — Interventions centre on delivering structured cognitive remediation and work-related social skills training sessions, i.e., patient training as a primary component.
yes yes yes → yes → no
shaky reasoning
✗ No consensus Initial: yes Requery: yes — The study includes cognitive remediation and work-related social skills training as a primary intervention component, involving 24 sessions of computer-based cognitive training and 24 group sessions of cognitive coping strategies and skills training. Thinking: no — This is primarily a vocational rehabilitation intervention focused on employment support (IPS), with cognitive training and social skills training as supplementary components to enhance employment outcomes, not as the primary intervention.
intervention_digital yes yes → yes → yes
shaky reasoning
✗ No consensus Initial: yes Requery: yes — The core intervention includes 24 sessions of computer-based cognitive training, which is a digital component central to the IPS plus intervention. Thinking: yes — The IPS-plus arm relies on computer-based cognitive remediation sessions, making digital technology a core component of that intervention.
no no no → no → no
shaky reasoning
✗ No consensus Initial: no Requery: no — While one arm includes computer-based cognitive training, the core intervention is Individual Placement and Support (IPS) which is an in-person vocational rehabilitation service delivered by employment specialists, making the digital component supplementary rather than the primary delivery mechanism. Thinking: no — While one arm includes computer-based cognitive training, the core intervention is employment support delivered by human specialists, not technology.
intervention_other no no → yes → no
shaky reasoning
✓ Unanimous Initial: no Requery: yes — The interventions involve behavioral approaches like vocational rehabilitation and cognitive/social skills training, which do not fit into the specified categories such as pharmacologic or device interventions. Thinking: no — The trial uses behavioral mental-health therapies (IPS with cognitive remediation and social skills training), fitting the psychological category.
yes no yes → yes → no
shaky reasoning
✓ Unanimous Initial: yes Requery: yes — This intervention involves vocational rehabilitation and employment support services combined with cognitive remediation and social skills training, which do not fit into any of the specified intervention categories. Thinking: no — The intervention includes psychological components (cognitive remediation, social skills training) and is a complex multi-component intervention.
outcome_symptom yes yes yes OK
outcome_qol yes yes yes OK
outcome_dignity no no no OK
outcome_cost no yes no
outcome_other yes yes yes OK
pharmacologic_sub N/A N/A N/A OK
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