| Protocol ID | NCT01871155 |
| Registration Date | 2013-06-06 |
| Status | completed |
| Sponsor | Dental Innovation Foundation Under Royal Patronage |
| Country | Thailand |
| Industry | not industry |
| Blinding | blinded |
| Center Type | singel-center RCT |
| Scope | national RCT |
| First Patient In | 2012-01-01 |
| Last Patient Out | 2012-08-01 |
| Publication | n |
| Gender % | ALL |
| Mean Age | 35 Years - 85 Years |
NCT01871155
Efficacy Study of Nutri-jelly Intake on Quality of Life in Head and Neck Cancer Patients Undergoing Radiotherapy
| Field |
OPENAI
gpt-4o Thinking: o3 3293ms / 8263 tok |
GLM
glm-5.1 5736ms / 8401 tok |
CLAUDE
claude-sonnet-4-20250514 Thinking: claude-opus-4-20250514 4941ms / 9609 tok |
Review |
|---|---|---|---|---|
| rct_type |
N/A
parallel RCT → N/A
shaky reasoning✓ Unanimous
Initial: parallel RCT
Requery: N/A — Allocation is non-randomized, hence no randomization design is described.
|
parallel RCT |
N/A
N/A → N/A
shaky reasoning✓ Unanimous
Initial: N/A
Requery: N/A — The study explicitly states Allocation: NON_RANDOMIZED, indicating this is not a randomized controlled trial.
|
– |
| cancer_status | Cancer | Cancer | Cancer | OK |
| non_cancer_spec | N/A | N/A | N/A | OK |
| setting_patient | outpatient | outpatient | outpatient | OK |
| setting_place |
other
hospital → hospital → other
shaky reasoning✓ Unanimous
Initial: hospital
Requery: hospital — The study involves patients undergoing radiotherapy, which is an inpatient or hospital-based treatment, indicating the intervention is delivered in a hospital setting.
Thinking: other — Nutri-jelly is consumed by patients receiving outpatient radiotherapy, so the intervention is delivered in an outpatient clinic rather than an inpatient hospital unit.
|
other |
other
other → other
shaky reasoning✓ Unanimous
Initial: other
Thinking: other — Patients receive radiotherapy as outpatients and self-administer the oral Nutri-jelly supplement, not requiring hospitalization.
|
OK |
| feasibility | fully powered RCT | fully powered RCT | fully powered RCT | OK |
| intervention_pharmacologic | no | no | no | OK |
| intervention_chemo_immuno_radio |
no
yes → yes → no
shaky reasoning✓ Unanimous
Initial: yes
Requery: yes — Radiotherapy is an active component being tested in this clinical trial.
Thinking: no — The study tests a dietary supplement (Nutri-jelly) rather than chemotherapy, immunotherapy, or radiation as the active intervention.
|
no |
no
no → no → no
shaky reasoning✓ Unanimous
Initial: no
Requery: no — The intervention being tested is Nutri-jelly (a nutritional supplement), not chemotherapy, immunotherapy, or radiation therapy - while patients are receiving radiotherapy, it is the standard treatment context, not the experimental intervention being studied.
Thinking: no — The intervention being tested is Nutri-jelly (a dietary supplement), while radiotherapy is just the clinical context in which patients are receiving standard care.
|
OK |
| intervention_complementary | no | no | no | OK |
| intervention_device | no | no | no | OK |
| intervention_psychological | no | no | no | OK |
| intervention_complex | no | no | no | OK |
| intervention_acp | no | no | no | OK |
| intervention_music | no | no | no | OK |
| intervention_screening | no | no | no | OK |
| intervention_palliative | no | no | no | OK |
| intervention_education | no | no | no | OK |
| intervention_digital | no | no | no | OK |
| intervention_other | yes | yes | yes | OK |
| outcome_symptom | no | no | no | OK |
| outcome_qol | yes | yes | yes | OK |
| outcome_dignity | no | no | no | OK |
| outcome_cost | no | no | no | OK |
| outcome_other | no | no | no | OK |
| pharmacologic_sub | N/A | N/A | N/A | OK |