| Protocol ID | NCT02655913 |
| Registration Date | 2016-01-14 |
| Status | completed |
| Sponsor | Clifford Hospital, Guangzhou, China |
| Country | China |
| Industry | not industry |
| Blinding | blinded |
| Center Type | singel-center RCT |
| Scope | national RCT |
| First Patient In | 2015-12-01 |
| Last Patient Out | 2018-08-01 |
| Publication | n |
| Gender % | ALL |
| Mean Age | 18 Years - 70 Years |
NCT02655913
Phase I-II Study of Vitamin C Infusion in Combination With Local mEHT on Non Small Cell Lung Cancer Patients
| Field |
CLAUDE
claude-sonnet-4-20250514 5482ms / 10826 tok |
GLM
glm-5.1 7684ms / 9462 tok |
OPENAI
gpt-4o Thinking: o3 3231ms / 9308 tok |
Review |
|---|---|---|---|---|
| rct_type | parallel RCT | parallel RCT | parallel RCT | OK |
| cancer_status | Cancer | Cancer | Cancer | OK |
| non_cancer_spec | N/A | N/A | N/A | OK |
| setting_patient | outpatient | outpatient | outpatient | OK |
| setting_place | hospital | hospital | hospital | OK |
| feasibility | fully powered RCT | fully powered RCT | fully powered RCT | OK |
| intervention_pharmacologic | yes | yes | yes | OK |
| intervention_chemo_immuno_radio | no | no | no | OK |
| intervention_complementary | yes |
yes
yes → yes
shaky reasoning✗ No consensus
Initial: yes
Requery: yes — Vitamin C (ascorbate) infusion is utilized in this trial as an alternative and complementary anticancer therapy.
|
no
no → no → yes
shaky reasoning✗ No consensus
Initial: no
Requery: no — The trial involves vitamin C infusion and modulated electro-hyperthermia, which are not classified as CAM modalities such as acupuncture, aromatherapy, massage, reflexology, yoga, meditation, Reiki, or herbal remedies.
Thinking: yes — High-dose intravenous vitamin C is an alternative/dietary supplement therapy, qualifying as a complementary modality.
|
|
| intervention_device | yes | yes | yes | OK |
| intervention_psychological | no | no | no | OK |
| intervention_complex | yes | yes | yes | OK |
| intervention_acp | no | no | no | OK |
| intervention_music | no | no | no | OK |
| intervention_screening | no | no | no | OK |
| intervention_palliative | yes | no | no | – |
| intervention_education | no | no | no | OK |
| intervention_digital | no | no | no | OK |
| intervention_other | no | no | no | OK |
| outcome_symptom | no | no | no | OK |
| outcome_qol | yes | yes | yes | OK |
| outcome_dignity | no | no | no | OK |
| outcome_cost | no | no | no | OK |
| outcome_other | yes | yes | yes | OK |
| pharmacologic_sub | other | other | other | OK |