| Protocol ID | NCT03110692 |
| Registration Date | 2017-04-12 |
| Status | completed |
| Sponsor | University of Pennsylvania |
| Country | United States |
| Industry | not industry |
| Blinding | blinded |
| Center Type | singel-center RCT |
| Scope | national RCT |
| First Patient In | 2016-02-10 |
| Last Patient Out | 2018-02-09 |
| Publication | y |
| Gender % | ALL |
| Mean Age | 18 Years - |
NCT03110692
Health System Initiative to Reduce Unnecessary Daily X-Ray Image Guidance During Palliative Radiation Treatment
| Field |
GLM
glm-5.1 10385ms / 8438 tok |
CLAUDE
claude-sonnet-4-20250514 Thinking: claude-opus-4-20250514 4935ms / 9621 tok |
OPENAI
gpt-4o Thinking: o3 4289ms / 8288 tok |
Review |
|---|---|---|---|---|
| rct_type | cross-over RCT | cross-over RCT | cross-over RCT | OK |
| cancer_status | Cancer | Cancer | Cancer | OK |
| non_cancer_spec | N/A | N/A | N/A | OK |
| setting_patient | outpatient | outpatient | outpatient | OK |
| setting_place |
other
hospital → other
shaky reasoning✓ Unanimous
Initial: hospital
Requery: other — The intervention (radiation treatment) is delivered across an outpatient network of 5 radiation oncology sites, which constitute ambulatory/outpatient care rather than an inpatient hospital admission.
|
other
hospital → other
shaky reasoning✓ Unanimous
Initial: hospital
Requery: other — This is a radiation oncology intervention delivered at outpatient radiation treatment facilities across the Penn Radiation Oncology network, which constitutes outpatient clinic settings rather than inpatient hospital care.
|
other
other → other
shaky reasoning✓ Unanimous
Initial: other
Requery: other — The intervention is delivered in outpatient settings within a network of radiation oncology clinics, not requiring hospital admission.
|
OK |
| feasibility | fully powered RCT | fully powered RCT | fully powered RCT | OK |
| intervention_pharmacologic | no | no | no | OK |
| intervention_chemo_immuno_radio |
no
yes → no
shaky reasoning✓ Unanimous
Initial: yes
Requery: no — The tested intervention is a behavioral quality improvement initiative to change prescribing defaults, not the radiation therapy itself which serves as the clinical context.
|
no
no → no → no
shaky reasoning✓ Unanimous
Initial: no
Requery: no — This study tests a behavioral intervention (default prescription template) to reduce imaging frequency during radiation treatment, not radiation therapy itself as the intervention being tested.
Thinking: no — The trial tests a behavioral intervention (default prescription template) to reduce imaging frequency during radiation treatment, not testing radiation therapy itself as the intervention.
|
no
no → yes → no
shaky reasoning✓ Unanimous
Initial: no
Requery: yes — The trial tests a behavioral intervention aimed at optimizing radiation therapy practices.
Thinking: no — The study tests a behavioral default template to reduce daily imaging during standard palliative radiation, not the radiation treatment itself as an experimental therapy.
|
OK |
| intervention_complementary | no | no | no | OK |
| intervention_device | no | no | no | OK |
| intervention_psychological | no | no | no | OK |
| intervention_complex | no | no | no | OK |
| intervention_acp | no | no | no | OK |
| intervention_music | no | no | no | OK |
| intervention_screening | no | no | no | OK |
| intervention_palliative |
no
no
shaky reasoning✓ Unanimous
Initial: no
|
no
yes → no
shaky reasoning✓ Unanimous
Initial: yes
Requery: no — This study tests a default prescription template to reduce unnecessary daily imaging during radiation treatment - the intervention is a health services/quality improvement initiative, not palliative care consultation or service delivery itself.
|
no
no → no
shaky reasoning✓ Unanimous
Initial: no
Requery: no — The intervention involves introducing a default prescription template in the palliative setting to reduce unnecessary imaging during radiation, not palliative care itself.
|
OK |
| intervention_education | no | no | no | OK |
| intervention_digital | no | no | no | OK |
| intervention_other | yes | yes | yes | OK |
| outcome_symptom | no | no | no | OK |
| outcome_qol | no | no | no | OK |
| outcome_dignity | no | no | no | OK |
| outcome_cost | yes | yes | yes | OK |
| outcome_other |
yes
no → yes
shaky reasoning✓ Unanimous
Initial: no
Requery: yes — The primary outcome measures the rate of daily imaging, which is a healthcare utilization and feasibility metric rather than a direct measure of patient symptoms, quality of life, dignity, or cost.
|
yes
yes → yes
shaky reasoning✓ Unanimous
Initial: yes
Requery: yes — The primary outcome measures healthcare utilization (daily imaging frequency) which is a feasibility/implementation metric rather than symptom, quality of life, dignity, or cost outcomes.
|
yes
yes → yes
shaky reasoning✓ Unanimous
Initial: yes
Requery: yes — The outcome measures the reduction of unnecessary daily imaging, which is a feasibility and process improvement metric, not covered by symptom, QoL, dignity, or cost categories.
|
OK |
| pharmacologic_sub | N/A | N/A | N/A | OK |