NCT03432832

✓ Unanimous Initial: yes Requery: yes — The EASE intervention is a multicomponent program that fundamentally combines individual therapy sessions with active parent involvement, community practice, and a secure website (e-Coach) designed to interact and augment overall treatment intensity.

✓ Unanimous Initial: yes Requery: yes — The EASE intervention combines multiple interacting components from different categories: behavioral therapy sessions with therapists, parent involvement/training, community practice sessions, and an online support platform (e-Coach), creating a multimodal approach that explicitly integrates individual therapy, family involvement, and technology-based supports. Thinking: no — EASE is a single behavioral intervention for emotion regulation delivered through multiple modalities (therapy sessions, parent involvement, online support), not distinct interacting components from different categories.

✓ Unanimous Initial: no Requery: no — The EASE program is a behavioral intervention focused on emotion regulation, mindfulness, and skill enhancement and does not combine distinct components from different categories. Thinking: no — EASE is a single-modality behavioral/psychological therapy (mindfulness-based skills training) even though it includes parent and web supports, so it lacks multiple distinct intervention types from different categories.

✓ Unanimous Initial: yes Requery: yes — The trial includes the Brief Psychiatric Rating Scale (BPRS) to measure psychiatric symptoms and the Emotion Dysregulation Inventory (EDI) to assess emotional reactivity.

✓ Unanimous Initial: no Requery: yes — The Brief Psychiatric Rating Scale (BPRS) is listed as a secondary outcome, which is a validated instrument that measures psychiatric symptoms including depression and anxiety.

✓ Unanimous Initial: yes Requery: yes — The primary outcome measures include the Emotion Dysregulation Inventory Reactivity Scale Short Form (EDI-SF), which evaluates emotional reactivity and regulation, directly addressing symptoms in the study population.

✓ Unanimous Initial: yes Requery: no — All outcomes measure symptom severity (emotion dysregulation, psychiatric symptoms, and overall clinical improvement), which falls under the symptom category.

✓ Unanimous Initial: yes Requery: no — All primary and secondary outcomes measure symptom severity and emotional regulation functioning, which fall under symptom-related categories.

✓ Unanimous Initial: no Requery: no — All outcomes focus on symptom improvement and quality of life through emotion regulation adjustment.