NCT04385160

Myeloproliferative Neoplasms (MPN) and COVID-19

Extracted Fields (from Registry)
Protocol IDNCT04385160
Registration Date2020-05-12
Statuscompleted
SponsorFROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS
CountryBulgaria, Croatia, France, Germany, Italy, Poland, Spain, United Kingdom, United States
Industrynot industry
Blindingunblinded
Center Typemulticenter RCT
Scopemultinational RCT
First Patient In2020-05-13
Last Patient Out2022-08-31
Publicationn
Gender %ALL
Mean Age18 Years -
LLM Classifications (Side-by-Side)
Field OPENAI
gpt-4o
4451ms / 8881 tok
CLAUDE
claude-sonnet-4-20250514
4466ms / 10304 tok
GLM
glm-5.1
9128ms / 9030 tok
Review
rct_type N/A N/A N/A OK
cancer_status Cancer Cancer Cancer OK
non_cancer_spec N/A N/A N/A OK
setting_patient mixed mixed mixed OK
setting_place other hospital → other
shaky reasoning
✓ Unanimous Initial: hospital Requery: other — The study involves follow-up of MPN patients diagnosed with COVID-19 in multiple centers, collecting data retrospectively and prospectively, indicating a mixture of settings including outpatient and potential hospital data collection, but no specific inpatient intervention delivery.
other other → other
shaky reasoning
✓ Unanimous Initial: other Requery: other — This is an observational study collecting data on MPN patients with COVID-19 across multiple European centers without specifying a single intervention delivery location, making it a mixed/community-based data collection study.
other hospital → other
shaky reasoning
✓ Unanimous Initial: hospital Requery: other — This is a multicenter observational study tracking outcomes across various settings (including outpatient and inpatient), rather than delivering a specific clinical intervention at a single fixed location.
OK
feasibility N/A N/A N/A OK
intervention_pharmacologic no no no OK
intervention_chemo_immuno_radio no no no OK
intervention_complementary no no no OK
intervention_device no no no OK
intervention_psychological no no no OK
intervention_complex no no no OK
intervention_acp no no no OK
intervention_music no no no OK
intervention_screening no no no OK
intervention_palliative no no no OK
intervention_education no no no OK
intervention_digital no no no OK
intervention_other no no no OK
outcome_symptom no no → no
shaky reasoning
✓ Unanimous Initial: no Requery: no — The trial focuses on thrombotic events and disease outcomes rather than specific symptoms or symptom scales.
no no → no
shaky reasoning
✓ Unanimous Initial: no Requery: no — This observational study focuses on clinical outcomes like thrombotic events, pulmonary embolism, mortality, and treatment interventions, but does not measure specific symptoms using validated symptom assessment instruments.
no yes
shaky reasoning
✓ Unanimous Initial: yes
OK
outcome_qol no no no OK
outcome_dignity no no no OK
outcome_cost no yes → no
shaky reasoning
✓ Unanimous Initial: yes Requery: no — The clinical trial focuses on clinical outcomes, patient characteristics, and mortality rates without any specific mention of cost-effectiveness or healthcare utilization.
no no → no
shaky reasoning
✓ Unanimous Initial: no Requery: no — The study measures clinical outcomes like thrombotic events, mortality, and disease progression without any cost-effectiveness analysis, healthcare utilization assessment, or cost-related measurements.
no no → no
shaky reasoning
✓ Unanimous Initial: no Requery: no — The clinical outcomes focus on clinical events like thrombosis, mortality, and ICU admission without measuring healthcare utilization or economic costs.
OK
outcome_other yes yes yes OK
pharmacologic_sub N/A N/A N/A OK
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