NCT05722847

Development of an Enhanced Risk Stratification System for Patients With Hospital-diagnosed Advanced Lung Cancer

Extracted Fields (from Registry)
Protocol IDNCT05722847
Registration Date2023-02-10
Statuscompleted
SponsorUNC Lineberger Comprehensive Cancer Center
CountryUnited States
Industrynot industry
Blindingunblinded
Center Typesingel-center RCT
Scopenational RCT
First Patient In2023-03-14
Last Patient Out2025-05-02
Publicationn
Gender %ALL
Mean Age18 Years -
LLM Classifications (Side-by-Side)
Field GLM
glm-5.1
6733ms / 9349 tok
CLAUDE
claude-sonnet-4-20250514
Thinking: claude-opus-4-20250514
4906ms / 10681 tok
OPENAI
gpt-4o
Thinking: o3
4041ms / 9200 tok
Review
rct_type N/A N/A N/A OK
cancer_status Cancer Cancer Cancer OK
non_cancer_spec N/A N/A N/A OK
setting_patient mixed outpatient mixed → mixed → outpatient
shaky reasoning
✓ Unanimous Initial: mixed Requery: mixed — The study includes patients who are initially hospitalized (inpatient) for their lung cancer diagnosis, then transitions to outpatient care with 90-day follow-up monitoring after hospital discharge. Thinking: outpatient — The intervention (PRO symptom monitoring, navigation, and palliative care) is delivered for 90 days AFTER hospital discharge via web/telephone, making this an outpatient study despite initial hospital diagnosis.
outpatient outpatient → outpatient → outpatient
shaky reasoning
✓ Unanimous Initial: outpatient Requery: outpatient — The intervention involves web- or telephone-based PRO symptom monitoring after hospital discharge, indicating outpatient status during the intervention phase. Thinking: outpatient — Intervention consists of post-discharge web/telephone symptom monitoring and supportive outpatient care, so patients are not admitted during the study treatment phase.
setting_place hospital hospital hospital OK
feasibility N/A N/A N/A OK
intervention_pharmacologic no no no OK
intervention_chemo_immuno_radio no no no OK
intervention_complementary no no no OK
intervention_device no no no OK
intervention_psychological no no no OK
intervention_complex no no no OK
intervention_acp no no no OK
intervention_music no no no OK
intervention_screening no no yes → no
shaky reasoning
✓ Unanimous Initial: yes Requery: no — This is an observational study developing a risk stratification system and implementing supportive care interventions, not testing a screening tool itself as the primary intervention.
no no → no
shaky reasoning
✓ Unanimous Initial: no Requery: no — The study evaluates supportive care feasibility based on risk stratification, not testing screening as an intervention.
OK
intervention_palliative no yes yes → no → no
shaky reasoning
✗ No consensus Initial: yes Requery: no — This is an observational study testing a risk stratification system and patient-reported outcome monitoring, where palliative care referral is just one component being measured as an outcome rather than the primary intervention being tested. Thinking: no — This observational study tests a risk stratification system for lung cancer patients where palliative care is one of several supportive services recommended for high-risk patients, not the intervention being evaluated.
no no → yes → yes
shaky reasoning
✗ No consensus Initial: no Requery: yes — The trial involves recommending palliative care as part of supportive care interventions for the high-risk group, making palliative care the intervention being tested. Thinking: yes — The study’s intervention involves a triggered supportive-care pathway that specifically recommends and measures receipt of palliative care consultation for high-risk patients.
intervention_education no no no OK
intervention_digital no yes yes
intervention_other no no no OK
outcome_symptom yes yes yes OK
outcome_qol no no no OK
outcome_dignity no no no OK
outcome_cost yes yes yes OK
outcome_other yes yes yes OK
pharmacologic_sub N/A N/A N/A OK
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