| Protocol ID | NCT05964959 |
| Registration Date | 2023-07-28 |
| Status | completed |
| Sponsor | Leiden University Medical Center |
| Country | Netherlands |
| Industry | not industry |
| Blinding | unblinded |
| Center Type | singel-center RCT |
| Scope | national RCT |
| First Patient In | 2023-06-15 |
| Last Patient Out | 2026-04-15 |
| Publication | n |
| Gender % | ALL |
| Mean Age | 18 Years - |
NCT05964959
Dry Mouth in Patients With a Life-limiting Condition or Frailty: the Effect of a Nurse-led Patient Education Program
| Field |
OPENAI
gpt-4o Thinking: o3 3961ms / 9969 tok |
CLAUDE
claude-sonnet-4-20250514 Thinking: claude-opus-4-20250514 8472ms / 11434 tok |
GLM
glm-5.1 6417ms / 10107 tok |
Review |
|---|---|---|---|---|
| rct_type |
Cluster RCT
Cluster RCT → Cluster RCT → N/A
shaky reasoning✗ No consensus
Initial: Cluster RCT
Requery: Cluster RCT — The trial mentions 'cluster based intervention', indicating randomization at a group level.
Thinking: N/A — Allocation is non-randomized, so despite mentioning clusters the study is not a randomized trial.
|
N/A
N/A → Cluster RCT → Cluster RCT
shaky reasoning✗ No consensus
Initial: N/A
Requery: Cluster RCT — The study is explicitly described as a 'cluster based intervention trial' in the brief summary, indicating randomization occurs at the group/cluster level rather than individual participant level.
Thinking: Cluster RCT — The brief summary explicitly states this is a 'cluster based intervention trial' where trained nurses deliver the intervention.
|
Cluster RCT |
|
| cancer_status | non-cancer | non-cancer | non-cancer | OK |
| non_cancer_spec | early palliative care | early palliative care | early palliative care | OK |
| setting_patient | outpatient | outpatient | mixed | – |
| setting_place | other | other | other | OK |
| feasibility | fully powered RCT | fully powered RCT | feasibility RCT | – |
| intervention_pharmacologic | no | no | no | OK |
| intervention_chemo_immuno_radio | no | no | no | OK |
| intervention_complementary | no | no | no | OK |
| intervention_device | no | no | no | OK |
| intervention_psychological | no | no | no | OK |
| intervention_complex | no | no | no | OK |
| intervention_acp | no | no | no | OK |
| intervention_music | no | no | no | OK |
| intervention_screening | no | no | no | OK |
| intervention_palliative |
no
no → no
shaky reasoning✓ Unanimous
Initial: no
Requery: no — The intervention is a nurse-led educational program for dry mouth management, not a palliative care consultation or team intervention.
|
no
yes → no
shaky reasoning✓ Unanimous
Initial: yes
Requery: no — This is a nurse-led educational program specifically for dry mouth management, not a palliative care consultation/referral/service delivery intervention.
|
yes | – |
| intervention_education | yes | yes | yes | OK |
| intervention_digital | no | no | no | OK |
| intervention_other | no | no | no | OK |
| outcome_symptom | yes | yes | yes | OK |
| outcome_qol | yes | yes | yes | OK |
| outcome_dignity | no | no | no | OK |
| outcome_cost | yes | yes | yes | OK |
| outcome_other | yes | yes | yes | OK |
| pharmacologic_sub | N/A | N/A | N/A | OK |