| Protocol ID | NCT06420206 |
| Registration Date | 2024-05-17 |
| Status | recruiting |
| Sponsor | M.D. Anderson Cancer Center |
| Country | United States |
| Industry | not industry |
| Blinding | unblinded |
| Center Type | singel-center RCT |
| Scope | national RCT |
| First Patient In | 2024-05-14 |
| Last Patient Out | 2027-02-02 |
| Publication | n |
| Gender % | ALL |
| Mean Age | 18 Years - |
NCT06420206
Goals of Care Discussion for Patients With Advanced Lung and Gastrointestinal Cancer in the Emergency Department of a Comprehensive Cancer Center
| Field |
CLAUDE
claude-sonnet-4-20250514 Thinking: claude-opus-4-20250514 5364ms / 9766 tok |
GLM
glm-5.1 8179ms / 8555 tok |
OPENAI
gpt-4o Thinking: o3 2814ms / 8405 tok |
Review |
|---|---|---|---|---|
| rct_type | N/A | N/A | N/A | OK |
| cancer_status | Cancer | Cancer | Cancer | OK |
| non_cancer_spec | N/A | N/A | N/A | OK |
| setting_patient | inpatient | inpatient | inpatient | OK |
| setting_place | hospital | hospital | hospital | OK |
| feasibility |
N/A
fully powered RCT → fully powered RCT → N/A
shaky reasoning✓ Unanimous
Initial: fully powered RCT
Requery: fully powered RCT — This is a non-randomized controlled trial with 200 participants designed to measure clinical effectiveness outcomes including acute care utilization, ICU admissions, and healthcare costs, indicating it's powered for meaningful clinical results rather than feasibility testing.
Thinking: N/A — Non-randomized interventional study, not an RCT
|
N/A
N/A → N/A
shaky reasoning✓ Unanimous
Initial: N/A
Requery: N/A — The study is a non-randomized interventional trial rather than a randomized controlled trial (RCT).
|
N/A
N/A → N/A → N/A
shaky reasoning✓ Unanimous
Initial: N/A
Requery: N/A — The study is non-randomized and interventional without random group assignment, indicating it is observational.
Thinking: N/A — This is a non-randomized interventional study rather than a randomized controlled trial.
|
OK |
| intervention_pharmacologic | no | no | no | OK |
| intervention_chemo_immuno_radio | no | no | no | OK |
| intervention_complementary | no | no | no | OK |
| intervention_device | no | no | no | OK |
| intervention_psychological | no | no | no | OK |
| intervention_complex | no | no | no | OK |
| intervention_acp | yes | yes | yes | OK |
| intervention_music | no | no | no | OK |
| intervention_screening | no | no | no | OK |
| intervention_palliative | yes | yes | yes | OK |
| intervention_education | no | no | no | OK |
| intervention_digital | no | no | no | OK |
| intervention_other | no | no | no | OK |
| outcome_symptom | no | no | no | OK |
| outcome_qol |
yes
yes → no → no
shaky reasoning✗ No consensus
Initial: yes
Requery: no — The primary outcome is listed as 'Quality Of Life Questionnaire' but no specific validated QoL instrument is identified, and the study focuses on healthcare utilization metrics rather than formal quality of life assessment.
Thinking: no — While 'Quality Of Life Questionnaire' is listed as primary outcome, no validated QoL instrument is specified and description shows 'N/A'.
|
yes
yes → yes
shaky reasoning✗ No consensus
Initial: yes
Requery: yes — The primary outcome includes a 'Quality Of Life Questionnaire' which implies the use of a standardized QoL instrument to measure quality of life as defined by the study's aim.
|
no
no → no → yes
shaky reasoning✗ No consensus
Initial: no
Requery: no — The trial mentions quality of life objectives but does not specify the use of any validated Quality of Life instruments.
Thinking: yes — The primary outcome is a Quality of Life Questionnaire, indicating measurement with a QoL instrument.
|
|
| outcome_dignity | no | no | no | OK |
| outcome_cost | yes | yes | yes | OK |
| outcome_other | yes | yes | yes | OK |
| pharmacologic_sub | N/A | N/A | N/A | OK |