NCT06420609

✓ Unanimous Initial: yes Requery: no — The Go-TAD intervention consists of 4 open-ended questions about death thoughts delivered during a medical visit, which is supportive conversation rather than a structured psychological therapy approach.

✓ Unanimous Initial: no Requery: no — The intervention involves general supportive conversations regarding death thoughts, not a structured psychological therapy.

✓ Unanimous Initial: no

✓ Unanimous Initial: yes Requery: no — While the intervention involves structured conversations about death thoughts with advanced cancer patients, it focuses on emotional distress and coping rather than the core ACP components of goals-of-care planning, advance directives, or care preferences.

✓ Unanimous Initial: no Requery: no — The intervention focuses on approaching death thoughts and emotional distress, not on structured Advance Care Planning.

✓ Unanimous Initial: no Requery: no — The Go-TAD intervention focuses on addressing death thoughts to reduce distress and is not a structured advance care planning tool for future medical decisions.

✓ Unanimous Initial: no Requery: no — The Go-TAD intervention involves asking open-ended questions about death thoughts during medical visits, which is a psychological intervention focused on communication and emotional support.

✓ Unanimous Initial: no Requery: no — The intervention fits the category of psychological as it involves addressing death thoughts to reduce emotional distress and improve the doctor-patient relationship.

✓ Unanimous Initial: yes

✓ Unanimous Initial: yes Requery: yes — The primary outcome measures emotional distress using the DME questionnaire (4-item visual numerical scale for mood, coping, and concerns), which is a specific symptom assessment instrument.

✓ Unanimous Initial: no Requery: yes — The primary outcome measures emotional distress, which is a validated symptom measure related to mental health.

✓ Unanimous Initial: yes Requery: yes — The trial uses the Palliative Outcome Scale (POS) as a secondary outcome, which is a symptom/distress measure explicitly listed in the classification guidelines.

✓ Unanimous Initial: no Requery: no — The study measures emotional distress, hopelessness, doctor-patient relationship, and quality of life, but does not specifically assess dignity, meaning in life, spiritual well-being, or existential themes using validated dignity-related instruments.

✓ Unanimous Initial: no Requery: no — The outcomes focused on emotional distress, hopelessness, doctor-patient relationship, and quality of life rather than existential/spiritual themes or measures of dignity.

✓ Unanimous Initial: yes Requery: no — The primary and secondary outcomes focus on general emotional distress, hopelessness, and the doctor-patient relationship, none of which specifically measure dignity, existential distress, or spiritual well-being using dedicated instruments.