NCT06765707

Symptom Monitoring Using Patient-Reported Outcomes to Optimize Medication Use

Extracted Fields (from Registry)
Protocol IDNCT06765707
Registration Date2025-01-09
Statusenrolling_by_invitation
SponsorMedical College of Wisconsin
CountryUnited States
Industrynot industry
Blindingblinded
Center Typemulticenter RCT
Scopenational RCT
First Patient In2025-06-23
Last Patient Out2029-08-01
Publicationn
Gender %FEMALE
Mean Age18 Years -
LLM Classifications (Side-by-Side)
Field GLM
glm-5.1
5698ms / 9340 tok
CLAUDE
claude-sonnet-4-20250514
6191ms / 10682 tok
OPENAI
gpt-4o
4405ms / 9185 tok
Review
rct_type cross-over RCT cross-over RCT cross-over RCT OK
cancer_status Cancer Cancer Cancer OK
non_cancer_spec N/A N/A N/A OK
setting_patient outpatient outpatient outpatient OK
setting_place other other
shaky reasoning
✓ Unanimous Initial: other
other other → other
shaky reasoning
✓ Unanimous Initial: other Requery: other — The intervention involves outpatient pharmacist consultations (face-to-face or virtual visits) and monthly symptom monitoring via online surveys or phone calls, which are delivered in clinic or community settings rather than requiring hospital admission.
other hospital → other
shaky reasoning
✓ Unanimous Initial: hospital Requery: other — The intervention involves both virtual and face-to-face visits with clinical pharmacists, making the primary setting outpatient clinical care, not requiring hospital admission or specific facility-based delivery.
OK
feasibility fully powered RCT fully powered RCT fully powered RCT OK
intervention_pharmacologic no no no OK
intervention_chemo_immuno_radio no no no OK
intervention_complementary no no no OK
intervention_device no no no OK
intervention_psychological no no no OK
intervention_complex no yes
shaky reasoning
✓ Unanimous Initial: yes
no yes → no
shaky reasoning
✓ Unanimous Initial: yes Requery: no — This is a single behavioral intervention consisting of pharmacist-delivered symptom monitoring and management, even though it has multiple components (monitoring + management), they are all part of one integrated behavioral/supportive care approach rather than combining distinct intervention types.
no no → no
shaky reasoning
✓ Unanimous Initial: no Requery: no — The intervention consists of a single modality approach focusing on pharmacist-led symptom monitoring and management based on patient-reported outcomes, without combining distinct interventions from different categories.
OK
intervention_acp no no no OK
intervention_music no no no OK
intervention_screening no no
shaky reasoning
✓ Unanimous Initial: no
no yes → no
shaky reasoning
✓ Unanimous Initial: yes Requery: no — The intervention being tested is a pharmacist-delivered symptom monitoring and management program to improve medication adherence, not a screening tool itself - the patient-reported outcomes are used as part of the symptom management intervention rather than being the screening intervention being evaluated.
no no → no
shaky reasoning
✓ Unanimous Initial: no Requery: no — The primary focus is on symptom monitoring and management to optimize medication adherence, not on testing a screening tool for palliative care needs.
OK
intervention_palliative no yes
shaky reasoning
✓ Unanimous Initial: yes
no no → no
shaky reasoning
✓ Unanimous Initial: no Requery: no — This is a behavioral intervention focused on symptom monitoring and pharmacist-led medication adherence support for breast cancer patients, not a palliative care consultation or service delivery intervention.
no yes → no
shaky reasoning
✓ Unanimous Initial: yes Requery: no — The trial focuses on symptom monitoring and pharmacist-led management for medication adherence, not palliative care as an intervention.
OK
intervention_education no no → no
shaky reasoning
✓ Unanimous Initial: no Requery: no — The trial primarily uses symptom monitoring with pharmacist-led management to address symptoms and barriers, rather than utilizing patient/caregiver education or training as a primary component.
no yes → no
shaky reasoning
✓ Unanimous Initial: yes Requery: no — This is a pharmacist-led symptom monitoring and management intervention focused on improving medication adherence, not a primarily educational program.
no no → no
shaky reasoning
✓ Unanimous Initial: no Requery: no — The primary focus of the trial is symptom monitoring and management to optimize medication adherence, not education or training.
OK
intervention_digital yes yes yes OK
intervention_other no no no OK
outcome_symptom yes yes yes OK
outcome_qol no no no OK
outcome_dignity no no no OK
outcome_cost no no no OK
outcome_other yes yes yes OK
pharmacologic_sub N/A N/A N/A OK
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