NCT06927635

✓ Unanimous Initial: other Requery: other — The study involves SBRT, a form of radiation therapy that is typically delivered in an outpatient clinic or ambulatory care setting, without requiring patient hospitalization.

✓ Unanimous Initial: hospital Requery: other — This is a single-center outpatient radiation therapy study where patients receive SBRT treatments at a medical facility, which represents an outpatient clinical setting rather than requiring hospitalization.

✓ Unanimous Initial: hospital Requery: other — The intervention involves Stereotactic Body Radiotherapy (SBRT) according to institutional standards, likely in a specialized clinic or outpatient setting rather than requiring hospital admission.

✓ Unanimous Initial: no

✓ Unanimous Initial: no Requery: no — The experimental intervention is Stereotactic Body Radiation Therapy (SBRT), which is a radiation treatment technique, not a drug or medication.

✓ Unanimous Initial: yes Requery: no — The experimental intervention involves stereotactic body radiotherapy (SBRT), which is not a pharmacologic intervention.

✓ Unanimous Initial: yes Requery: yes — The secondary outcomes include the assessment of toxicity differences between arms using CTCAE v5.0, which is a validated instrument for evaluating adverse events and symptoms.

✓ Unanimous Initial: no Requery: no — The primary outcomes focus on feasibility and PSA changes, while secondary outcomes measure disease control, survival, toxicity via CTCAE, and quality of life via EORTC QLQ-C30, but none specifically assess individual symptoms using validated symptom measurement instruments. Thinking: no — The study uses EORTC QLQ-C30 for quality of life and CTCAE for toxicity grading, but does not include any validated symptom assessment instruments.

✓ Unanimous Initial: no Requery: no — The clinical trial does not involve any primary or secondary outcome measures that assess symptoms using symptom-specific instruments. Thinking: no — The listed outcomes assess PSA, imaging, toxicity (CTCAE), and QoL (EORTC) but include no validated symptom-specific instruments such as pain, fatigue, or mood scales.

✓ Unanimous Initial: N/A

✓ Unanimous Initial: N/A Requery: N/A — The primary intervention is Stereotactic Body Radiation Therapy (SBRT), which is a form of radiotherapy, not a pharmacologic intervention.

✓ Unanimous Initial: chemotherapy Requery: N/A — The intervention in this clinical trial is stereotactic body radiotherapy, which is not pharmacologic.