NCT07063862

✓ Unanimous Initial: early palliative care Requery: early palliative care — The study targets patients with advanced illness receiving palliative care regardless of specific disease type, focusing on early integration of palliative care for psychological and existential distress management. Thinking: N/A — Study targets palliative care patients with various advanced illnesses (2-12 months life expectancy) without focusing on a specific disease category or early integration of palliative care.

✓ Unanimous Initial: N/A Requery: early palliative care — The study targets the early integration of palliative care for patients with advanced illness experiencing psychological distress and is not limited to one specific disease. Thinking: N/A — Population includes mixed advanced illnesses including cancer, so category not applicable.

✓ Unanimous Initial: N/A Requery: N/A — The study targets patients with 'advanced illness' and 'chronic illness' in a palliative care setting, which includes a general and mixed non-cancer population rather than focusing on a specific organ system or single disease category.

✓ Unanimous Initial: no Requery: no — Psilocybin is a pharmaceutical psychedelic medication, not a complementary or alternative medicine modality like acupuncture, aromatherapy, massage, or herbal remedies.

✓ Unanimous Initial: yes Requery: no — The trial is focused on psilocybin microdosing, which is a psychedelic medication intervention, not one of the CAM modalities listed such as acupuncture or yoga.

✓ Unanimous Initial: no Requery: no — The intervention is psilocybin, which is a pharmacological drug and not listed as a complementary and alternative medicine (CAM) modality.